Multivariate analysis showed that the independent risk factors for LNM in GC were tumor size (OR: 2.058; P = 0.000), CT findings (OR: 1.969; P = 0.000), grade (OR: 0.479; P = 0.000), Hb (OR: 1.211; P = 0.005), CEA (OR: 1.111; P = 0.017), and CA19-9 (OR: 1.040; P = 0.033) (Table 2). This evidence concerns the gene GSTM1 and neoplasm.