CD19 and neoplasm: In another example of expanding and enhancing the persistence of CAR-T cells, patient-derived antigen-presenting cells were transduced with a lentiviral vector coding a truncated CD19 (CD19t) (107) and were infused into patients at high risk of short CAR-T cell persistence, such as low antigen tumor burden, rapid CAR-T contraction, or an early loss of B cell aplasia.