Data showed that overexpression of SRD5A1 was remarkably related to pathological grade (χ2 = 9.044, P = 0.004), lymph node metastasis (χ2 = 9.873, P = 0.002), distant metastasis (χ2 = 5.953, P = 0.021), and survival status (χ2 = 6.787, P = 0.034). Here, SRD5A1 is linked to metastatic malignant neoplasm in the lymph nodes.