LAG3 and neoplasm: Although they presented a significantly higher score of overall Th1 T cells (p = 0.05) and cytotoxic NK CD56dim cells (p = 0.04), the presence of exhausted CD8+ T cells suggest that T cells are recruited to the tumor site but lack activation as indicated by the gene expression of biomarkers indicative of T cell exhaustion such as CD8, CD244, EOMES, and LAG3.