VEGFA and neoplasm: During the progression of ovarian cancer, tumors could promote angiogenesis by secreting angiogenic factors such as vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and platelet-derived growth factor (PDGF), thereby promoting the neoformation of tumor blood vessels and, in turn, metastasis of ovarian cancer (9–11).