The radiosensitization of PTEN has also been reported in previous literature: Rosser et al. identified forced expression of PTEN as a valuable approach to achieve radiosensitization in prostate cancer cells (68); multiple studies confirmed that the radioresistance of nasopharyngeal carcinoma could be enhanced by suppressing the expression of PTEN (69–71); consistent conclusions were obtained in the corresponding researches of non-small cell lung carcinoma (72), hepatocellular carcinoma (73), and esophageal cancer (74). This evidence concerns the gene PTEN and Familial prostate cancer.