LATS1 and neoplasm: To explore the relationship between LATS1/2 and a tumor microenvironment in advanced GC, we used tumor immune-related markers including CD8, FOXP3, and CD163, representing CD8+ T cells, FOXP3+ Treg cells, and CD163+ M2 macrophages, respectively, and all played important roles in a tumor immune microenvironment (15–20).