Similarly, all three treatment arms had significantly lower mean tumor weight compared to control (SAM, 0.42 g, p < 0.05; anti-PD-1, 0.37 g, p < 0.01; and control, 0.68 g), and the SAM+anti-PD-1 group had significantly lower mean tumor weight (0.20 g) compared to control (p < 0.0001) and SAM (p < 0.05) (Figure 2C). Here, PDCD1 is linked to neoplasm.