We analyzed a few of the top DEGs (NRP2, CAPN3, DMBT1, BRAF, DDIT3, PPP1R3C, NF1) using The UCSC Xena platform (44) that has large number of RNA-seq data of normal tissue from healthy individuals (GTEx) and primary tumor and metastatic tissue data from melanoma patients (TCGA). The gene discussed is PPP1R3C; the disease is melanoma.