Highest sensitivities were reached by the SARS-CoV-2-IgG test by Abbott, the Elecsys® Anti-SARS-CoV-2 test by Roche (both N-protein-based tests) and the Anti-SARS-CoV-2-ELISA IgG by Euroimmun (S1-protein-based) while the EDITM Novel Coronavirus COVID-19 IgG ELISA showed a lower sensitivity. Here, PSMD1 is linked to COVID-19.