Apart from causing T2DM, the associated disrupted balance of hormones and glucose, i.e., the raised levels of insulin and glucose along with elevated adipocyte cytokines, is thought to lead to abnormal lipid profiles, functional atherosclerosis, hypertension, and vasculitis, all of which contribute towards development and advancement of CVDs [19-21]. The gene discussed is INS; the disease is type 2 diabetes mellitus.