Both conditions may possibly have common genetic pathways, since they have four shared risk loci, interleukin 18 receptor accessory protein (IL18RAP), protein tyrosine phosphatase, non-receptor type 2 (PTPN2), T-cell activation GTPase activating protein (TAGAP), and pseudouridylate synthase 10 (PUS10), which have been reported in CeD and CD [4]. This evidence concerns the gene TAGAP and Cowden disease.