HOTTIP and head and neck squamous cell carcinoma: Furthermore, qRT-PCR results showed that HOTTIP and LINC00460 were upregulated (Figs. 8W and 8X), hsa-miR-206 was downregulated (Fig. 8Y) to varying degrees in many HNSCC cell lines (HN4, HN6, Cal27, HN30, SCC9, and SCC25).