TP53 and head and neck squamous cell carcinoma: Second, we comprehensively analyzed the relationship between the prognosis model and each RNA included in the prediction model and conventional clinicopathological features (including TNM stage and histological grade) and specific HNSCC clinicopathological features (including TP53 mutation status, ALI, HPV status, PNI, and ECS) to further verify the significant correlation with survival and clinical therapeutic outcomes.