In hepatocellular carcinoma, LINC00665 regulates cell cycle pathways [11], whereas in lung adenocarcinoma, it acts as a ceRNA and binds miR-98, subsequently activating the aldo–keto reductase family 1 member B10 (AKR1B10)–extracellular-signal-regulated kinase (ERK)-signaling pathway [12]. This evidence concerns the gene AKR1B10 and lung adenocarcinoma.