Although DPR inclusions are widely distributed in the brain regions of C9orf72-associated ALS/FTD patients, few inclusions are found in the spinal cord in C9orf72-associated ALS from post-mortem studies, challenging their contribution to C9orf72-associated ALS cases (Gomez-Deza et al., 2015). The gene discussed is C9orf72; the disease is frontotemporal dementia.