To further validate the expression of these RBPs in BLCA, we analyzed immunohistochemistry data from the Human Protein Atlas (HPA) database5 to show that FLNA, FASTKD3, and POU5F1 were significantly decreased in BLCA compared with normal urinary bladder tissue (Figures 4A–C). Here, POU5F1 is linked to bladder transitional cell carcinoma.