A two-stage meta-analysis found that glycoprotein non-metastatic melanoma protein B (GPNMB)/7p15 was associated with PD onset (International Parkinson's Disease Genomics Consortium (IPDGC) Wellcome Trust Case Control Consortium 2 (WTCCC2)., 2011). This evidence concerns the gene GPNMB and late-onset Parkinson disease.