One study (121) evaluated datasets from the Genotype-Tissue Expression (GTEx) project, the cancer genome atlas (TCGA) program and the human protein atlas (HPA) database to evaluate ACE2 expression in 31 normal human tissues, comparing men versus women and younger (ages = 49 years) versus older (ages = 49 years) individuals and further correlating ACE2 expression with immune signature enrichment (CD8+ T cells, IFN response, B cells, and NK cells) across tissues. Here, ACE2 is linked to cancer.