CD38 and B-cell chronic lymphocytic leukemia: This was shown not only for chronic lymphocytic leukemia (CLL) upon rituximab treatment, where a partial loss of CD20 from CLL B cells accompanied trogocytosis events by neutrophils (160), but also anti-CD38 therapy with daratumumab directed against multiple myeloma (MM) which led to monocyte- and neutrophil-mediated shaving of CD38 from MM cells (161).