In addition, the Trp64Arg polymorphism in ADRB3 (β3-AR gene) was reported to be associated with susceptibility to endometrial cancer and decreased risk for breast cancer, especially when associated to Gln27Glu polymorphism in ADRB2 (β2-AR gene) (92, 93). The gene discussed is ADRB2; the disease is breast carcinoma.