TNNI3 and heart failure: Several cardiac parameters increased sharply, LDH [580 U/L (IQR, 447–696)], cardiac troponin I (cTnI) [0.07 ng/mL (IQR, 0.02–0.30)], as well as and pro-B-type natriuretic peptide (pro-BNP) [498 pg/mL (IQR, 241–1,726)], which indicated the heart function disorder, even heart failure in patients with severe COVID-19.