IL6 and COVID-19: Early clinical (fever, confusion) and laboratory (blood hyperferritinemia, lymphopenia, prolonged prothrombin time, elevated lactate dehydrogenase, elevated IL-6, elevated C-reactive protein, elevated soluble CD25) results from critically ill COVID-19 patients suggest the presence of a CSS causing ARDS and multi-organ failure (23, 72, 103) as seen with SARS-CoV and MERS-CoV infection (68).