Research looking into the maturation of dendritic cells (DCs) from lung cancer biopsies shows that DCs consist of three types, i.e., CD11chigh mDCs, CD11c– pDCs and CD11cint mDCs, in terms of their expression levels of CD11c, and most tumor-infiltrating DCs (TIDC) are “semi-mature” or even immature (58). The gene discussed is ITGAX; the disease is lung cancer.