More recently, atezolizumab was approved for several indications, such as in combination with abraxane for patients with PD-L1-positive metastatic triple-negative breast cancer (PD-L1–positive TNBC), in combination with chemotherapy for the initial treatment of adults with extensive-stage small-cell lung carcinoma (SCLC), and in combination with abraxane and carboplatin for the initial treatment of metastatic non-squamous NSCLC (Table 2). This evidence concerns the gene CD274 and non-small cell lung carcinoma.