Furthermore, the inhibition of S-to-G2/M phase transition in HFLS-RA cells mediated by the depletion of NEAT1 was partially restored by cotransfecting NEAT1 siRNAs and miR-410-3p inhibitor (p < 0.001, Figures 6C,D) or pcDNA-YY1 (p < 0.001). This evidence concerns the gene NEAT1 and rheumatoid arthritis.