NEAT1 and rheumatoid arthritis: Figure 4A shows the ENCORI-predicted binding sites for miR-410-3p on NEAT1. Dual-luciferase assays revealed binding between NEAT1 and miR-410-3p in HFLS-RA cells. HFLS-RA cells transfected with NEAT1-WT and miR-410-3p mimics showed significant decrease in relative luciferase activity as compared with luciferase intensities in NEAT1-MUT-transfected HFLS-RA cells (p = 0.0192, Figure 4B).