As shown in Figures 5A,B, siRNA-induced NEAT1 downregulation-mediated suppression of HFLS-RA cell proliferation was partially rescued by the cotransfection of NEAT1 siRNAs and miR-410-3p inhibitor (p < 0.01), or NEAT1 siRNAs and pcDNA-YY1 (p < 0.05). The gene discussed is YY1; the disease is rheumatoid arthritis.