It was also reported that high infiltration by TAMs at baseline was significantly associated with adverse outcome (PFS: 1.9 vs. 3.7 months, p = 0.045; OS: 4.8 months vs. NR, p = 0.027) and increased tumor infiltration by CD8+ T cells compared to baseline was significantly associated with better PFS (p = 0.011). Here, CD8A is linked to neoplasm.