The main aspect favoring the autoimmune etiology of MS consists of the presence of activated IFN-producing T helper 1 (Th1) cells, that recognize peptides of the myelin sheath, including myelin basic protein (MBP), proteolipid protein (PLP), and myelin oligodendrocyte glycoprotein (MOG) (80). The gene discussed is IFNA1; the disease is myeloid sarcoma.