TP53 and Ehlers-Danlos syndrome, musculocontractural type: This model is supported by scientific evidence, such as the presence of TP53 and BRAF mutations in differentiated and undifferentiated carcinomas, including ATCs (13), but it cannot explain the presence of specific RET/PTC rearrangements and PAX8/PPARγ gene fusion that may occur in ATCs (14).