Univariate analysis was performed for patients' age, sex, tumor size, stage, treatment modalities, B symptoms, serum LDH level, IPI score, administration of rituximab, BCL-2 protein expression level, MYC protein expression level, Myc/Bcl-2 protein co-expression, Hans classification, Ki-67, and presence of Hashimoto's thyroiditis, as listed in Table 1. This evidence concerns the gene MYC and neoplasm.