Moreover, in neither group affected by thyroid dysfunction or autoimmunity, thyroid hormone levels (TSH, fT4, fT3), TPO-AB levels, urinary iodine excretion, or thyroid volume accounted for a significant proportion of variance in KINDL-R or SDQ-TD scores nor did these variables show a significant (linear) relationship with HRQoL or mental health (Table 4). This evidence concerns the gene TPO and Autoimmunity.