We observed a significant increase (Mann–Whitney test: p = 0.001) in the LRRK2+/PD+ group (median: 1.74, IQR: 1.38–3.30) compared to the LRRK2+/PD− group (median: 0.95, IQR: 0.88–1.31) (Figure 1C). Here, LRRK2 is linked to Parkinson disease.