Moreover, acromegaly treatment and improved diabetes control can also result in a difference between LPL mRNA protein level (Simsolo et al., 1992, 1995), and Isoproterenol and insulin could regulate Lpl gene expression by affecting Lpl transcription and steady-state mRNA levels, respectively, suggestive of a post-transcriptional effect (Raynolds et al., 1990). This evidence concerns the gene LPL and diabetes mellitus.