In obese people, elevated miR-27 levels in the blood have been associated with higher TG and LDL-C levels and lower HDL-C levels (Can et al., 2016); moreover, it has been suggested that miR-27b can accelerate the development of arteriosclerosis by reducing the expression of PPARγ, thereby inducing perivascular adipose tissue hypertrophy (Chen et al., 2012). This evidence concerns the gene PPARG and arteriosclerosis disorder.