CCL2 and congenital secretory chloride diarrhea 1: In addition, L1-10 treatment downregulated endothelial adhesion molecules VCAM-1, ICAM-1 and monocyte chemoattractant protein 1 (MCP-1), which was also observed in other CLD models including CCl4 treatment and bile duct ligation (Lefere et al., 2019).