PPARG and cancer: The expression of PPARγ is downregulated in cancer cells (Lecarpentier et al., 2017) and PPARγ expression has been found to be an independent prognostic factor for overall and gastric cancer specific mortality in patients with intestinal-type gastric cancer with PPARγ-positive tumors resulting in lower overall and cancer-specific mortalities than PPARγ-negative tumors (Cho et al., 2015).