NR4A1 and atherosclerosis: The orphan nuclear receptor Nur77 is a protein encoded by NR4A1 and plays an important regulatory role in cell proliferation, apoptosis, differentiation, inflammation, atherosclerosis, metabolism, DNA repair, and tumorigenesis (Chintharlapalli et al., 2005; Lee et al., 2009; Boudreaux et al., 2012).