INS and hydrops fetalis: Only, treatment with A-1317 decreased insulin levels compared to HF/E rats and fasting blood glucose compared to CT/E, HF/E, HF/Ang-(1–7) and increased HOMA-β compared to CT/E and HF/Ang-(1–7) rats and QUICKI compared to HF/E and HF/Ang-(1–7) rats (Figures 1C, E, G, H).