In humans, SDK1 mutations are frequently observed in malignant mesothelioma (Cadby et al., 2013), adrenocortical carcinoma (Juhlin et al., 2015), gastric carcinoma (Rokutan et al., 2016), and lung adenocarcinoma (Mäki-Nevala et al., 2016), raising that possibility that the mutations are related to the etiology of some types of cancers. The gene discussed is SDK1; the disease is cancer.