Tuwaig et al. (2017) reported an association between poor SSI-ICM scores (−10 dB SNR) and atrophy in the right Heschl’s gyrus cortical thickness and thinner right parahippocampal and entorhinal cortices, bilateral precuneus, occipital cortex, left inferior parietal lobule, inferior and mid temporal gyri on structural magnetic resonance imaging (MRI), after adjusting for age, gender, education, pure-tone hearing, and APOE ε4 status. Here, APOE is linked to Atrophy.