We found that 24 of the 75 genes previously classified as unknown by Erdmann et al.69 were differentially expressed between cell populations in carotid plaques, and included 3 genes that also showed association with CAD (CHD13, SNRPD2, and ARHGEF26; Table III in the Data Supplement) in our analysis. This evidence concerns the gene ARHGEF26 and coronary artery disorder.