IL1B and neoplasm: It is plausible that senescence modulates the tumour‐suppressive immune response via SASP, since senescent human melanocytes upregulate the expression of the major histocompatibility complex (MHC) class II antigen presentation apparatus in response to secreted IL‐1β, thus enhancing T‐cell proliferation in vivo, which correlates with better prognosis in melanoma patients [147].