DNAJC5 and malaria: Malaria-specific MBCs are elicited at levels comparable to conventional licensed vaccines121 and can persist in naturally infected and travellers to endemic regions.122 Like antibodies, malaria MBCs appear to increase with age and exposure.123 Studies have demonstrated that Pf-specific MBCs target PE stage antigens, and existing antibodies to CSP, LSA-1 and TRAP may protect against clinical malaria in an endemic setting.105,124 Current literature does not indicate the magnitude of humoral reaction to other malaria PE antigens or if PE-specific MBCs are linked to protective immunity.