It has been shown that by means of tumour-specific tropism of MSCs can be transduced to deliver anticancer agents such as interleukins (IL-2, IL-7, IL-18, and IL-12), TRAIL, and interferon (IFN-β and IFN-γ) directly to glioma sites to kill tumour cells or to regulate immune responses [2, 4, 35, 36]. This evidence concerns the gene IL18 and glioma.