Many clinical trials and meta-analyses have revealed that treatment with statins, which are 3-hydroxy-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, targets a reduction in low-density lipoprotein cholesterol (LDL-C) and thereby decreases the risk of coronary heart disease (CHD) and all-cause mortality [1]. The gene discussed is HMGCR; the disease is coronary artery disorder.