De novo, monoallelic variants in SCN2A (Nav1.2), SCN3A (Nav1.3), and SCN8A (Nav1.6) are linked to other DEEs, including Ohtahara syndrome and early infantile epileptic encephalopathy type 13 (EIEE13).5, 6, 7, 8. The gene discussed is SCN2A; the disease is developmental and epileptic encephalopathy, 13.