ABCG5 and ABCG8, originally referred to as sterolin‐1 and‐2, were first identified in patients with the rare genetic disease sitosterolemia, a disorder of sterol absorption and secretion that elevates plant sterol levels in plasma and tissues [14, 15, 16, 17, 18, 19, 20, 21]. The gene discussed is ABCG5; the disease is sitosterolemia.