Further analysis revealed that the m5C methylation level and expression level of H19 RNA in HCC patients are significantly (p < 0.001) associated with the differentiation stages of tumors (Tables 1 and 2), indicating that abnormal NSUN2-mediated m5C modification of H19 lncRNA links to poorly differentiated hepatocellular carcinoma. The gene discussed is H19; the disease is hepatocellular carcinoma.