We performed multiplex immunofluorescence and immunohistochemical staining to analyze the spatial composition of tumor- and immune cells (T-Helper, CTLs, Tregs, B-cells, M1, and M2 macrophages) and immune evasion mechanisms (PD-L1, PD-1, and MHC class I) in 184 patients who received first-line chemotherapy. Here, CD274 is linked to neoplasm.