MAPK8 and metabolic dysfunction-associated steatohepatitis: Shedding light on this matter, Zhao et al.84 noticed that palmitoylation of CD36 facilitated fatty acid uptake, impaired FAO, activated the pro-inflammatory JNK/NF-κB pathway and enhanced lipid accumulation in hepatocytes, whereas inhibition of CD36 palmitoylation protected mice from developing NASH and inhibited the JNK signalling in hepatocytes.