There is a greater immune response during this phase involving the release of C-X-C motif chemokine ligand 10 (CXCL-10) and interferons (IFN-β and IFN-λ) from the virus-infected cells.27 The majority of patients do not progress beyond this phase as the mounted immune response is sufficient to contain the spread of infection. Here, CXCL10 is linked to infection.