Four days post infection, we confirmed the presence of MHC-IIlow monocytes in infected animals, and the results of the EdU proliferation assay revealed that lymphocytes from these animals were less proliferative than lymphocytes from control animals (1.74 ± 1.43% vs 10.21 ± 11.12%, p = 0.0079), as shown in Figure 4A, D. Using antibodies, we observed that this reduction in proliferation was more pronounced for CD4+ T cells (0.36 ± 0.36% vs 1.59 ± 0.86%, p = 0.0317) than for CD4− T cells (1.77 ± 1.21% vs 8.7 ± 10.2%, p = 0.095). Here, CD4 is linked to infection.