On immunohistochemistry (IHC), all 7 cases expressed vascular markers CD31, CD34 and ERG (Figs. 2 and 3 c, d) confirming the endothelial lineage of tumor cells and were negative for epithelial markers of CK AE1/AE3, Cam 5.2, CK7 and CK 20, Glypican3 and Hep par1. The gene discussed is KRT7; the disease is neoplasm.